Objective:To investigate the effect of functional electrical stimulation (FES) on brain function by using functional magnetic resonance imaging (fMRI), and further explore the Li-Po Li-ion mechanism of FES on central nervous system rehabilitation in patients with sub-cortical stroke.Methods:Ten subjects were recruited in the study, including five s
Signaling events affecting thymic selection of un-manipulated polyclonal natural CD25(+)foxp3(+) regulatory T cells (nTreg) have not been established ex vivo.Here, we report a higher frequency of phosphorylated STAT-5 (pSTAT-5) in nTreg cells in the adult murine thymus and Adhesive to a lesser extent in the periphery, compared to other CD4(+)CD8(-)
Abstract Background Many well-represented domains recognize primary sequences usually less than 10 amino acids in length, called Short Linear Motifs (SLiMs).Accurate prediction of SLiMs has been difficult because they are short (often Results Our combined approach revealed that SLiMs are highly conserved in proteins from functional classes that are
BACKGROUND:The aim of this study was to investigate the current surgical management strategy for bilateral breast cancer (BBC) patients and to assess the changes in this strategy in Original China.METHODS:This is a retrospective review of all patients with early-stage BBC who underwent surgical treatment at the Fudan University Shanghai Cancer Cent
Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement.To understand this process mechanistically, we investigated two Saccharomyces cerevisiae TFs, Reb1 and Cbf1.We sh